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Healthou_The Effect of Creatine Supplementation on Strength Recovery After Anterior Cruciate Ligament (ACL) Reconstruction

A Randomized, Placebo-Controlled, Double-Blind Trial

  1. Timothy F. Tyler*, 
  2. Stephen J. Nicholas, 
  3. Elliott B. Hershman,
  4. Beth W. Glace, 
  5. Michael J. Mullaney, and 
  6. Malachy P. McHugh
  1. From NISMAT at Lenox Hill Hospital, New York, New York
  1. Address correspondence to Timothy F. Tyler, NISMAT at Lenox Hill Hospital, 130 East 77th Street, New York, NY 10021.

Abstract

Background: Creatine supplementation has been shown to augment training-induced strength gains. The purpose of this study was to examine the effect of creatine supplementation on recovery of muscle strength after anterior cruciate ligament (ACL) reconstruction.

Hypothesis: Creatine supplementation will facilitate strength gains after ACL reconstruction.

Study Design: Double-blind, prospective, and randomized clinical trial.

Methods: Sixty patients were randomized into creatine or placebo groups. Quadriceps and hamstring strength and power were measured isokinetically. Hip flexor, abductor, and adductor strengths were measured with a handheld dynamometer prior to surgery and at 6 weeks, 12 weeks, or 6 months after surgery.

Results: From 6 weeks to 12 weeks after surgery, there were significant increases in strength on the involved side for knee extension (47%), knee flexion (27%), hip flexion (20%), hip abduction (9%), and hip adduction (17%). These strength improvements were unaffected by creatine supplementation with similar effects in the creatine and placebo groups. From 6 weeks to 12 weeks after surgery, there were significant increases in power on the involved side for knee extension (46%) and knee flexion (26%), but these effects were not affected by creatine supplementation. At 6 months, creatine supplementation did not affect outcome as measured by the single leg hop test for distance or the knee outcome score.

Conclusions: The results demonstrate that patients do not benefit from creatine supplementation during the first 12 weeks of rehabilitation after ACL reconstruction.

from source:http://ajs.sagepub.com/content/32/2/383.short


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